Food Hypersensitivity and Metabolism of Xenobiotic Compounds 39
نویسندگان
چکیده
منابع مشابه
Xenobiotic Metabolism and Gut Microbiomes
Humans are exposed to numerous xenobiotics, a majority of which are in the form of pharmaceuticals. Apart from human enzymes, recent studies have indicated the role of the gut bacterial community (microbiome) in metabolizing xenobiotics. However, little is known about the contribution of the plethora of gut microbiome in xenobiotic metabolism. The present study reports the results of analyses o...
متن کاملThe steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism
The steroid and xenobiotic receptor (SXR) (also known as pregnane X receptor or PXR) is a nuclear hormone receptor activated by a diverse array of endogenous hormones, dietary steroids, pharmaceutical agents, and xenobiotic compounds. SXR has an enlarged, flexible, hydrophobic ligand binding domain (LBD) which is remarkably divergent across mammalian species and SXR exhibits considerable differ...
متن کاملSymbolic Inference of Xenobiotic Metabolism
We present a new symbolic computational approach to elucidate the biochemical networks of living systems de novo and we apply it to an important biomedical problem: xenobiotic metabolism. A crucial issue in analyzing and modeling a living organism is understanding its biochemical network beyond what is already known. Our objective is to use the available metabolic information in a representatio...
متن کاملSalicylate Food Intolerance and Aspirin Hypersensitivity in Nasal Polyposis
Background: A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). Objective: To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. Methods: A cross sectional multicenter study was d...
متن کاملBiodegradation of Xenobiotic Compounds: An Overview
The continuous accumulation of recalcitrant xenobiotic compounds into the ecosystem released from various sources caused a serious global concern. Xenobiotics compounds are carcinogenic, mutagenic, causing teratogenic effect and persist over a long period of time in the environment. Therefore there is an urgent need for the detoxification of these compounds. Biodegradation is a technique that e...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-00060